Aggressive Posterior Retinopathy of Prematurity (AP-ROP)

Synonym: Rush type of ROP

Incidence: 2.5% of cases of ROP

Features:

(1) posterior location (zone I or posterior zone II)

(2) PLUS disease, with vessels showing dilatation and tortuosity out of proportion to the peripheral retinopathy

(3) rapidly progressive, reaching Stage 5 if untreated

Additional findings may include:

(1) retinal hemorrhages at the junction between vascularized and avascular retina

(2) a circumferential vessel

(3) persistent tunica vasculosa lentis

(4) flat growth of neovascularization

(5) retinal detachment