Amnioinfusion may be associated with adverse events, which can affect the mother and/or fetus.
Patient selection: pregnant woman and fetus
Adverse effects may include:
(1) infection
(2) bleeding (amniotic, placental, uterine, fetal, other)
(3) premature rupture of the membranes (PROM)
(4) threatened preterm delivery
(5) fetal bradycardia
(6) non-reassuring fetal status
(7) abruption
(8) amniotic embolism
(9) organ injury (uterine for maternal; abdominal for fetus)
(10) maternal pulmonary edema
(11) maternal pulmonary embolism
(12) pain
(13) secondary amniotic band syndrome
(14) fetal or maternal death
Risk factors for adverse events:
(1) increased numbers of punctures
(2) large volume of infusate
(3) expertise level of providers
(4) poor visualization on imaging
(5) maternal factors (hypercoagulability, other)
