Description

Caffeine or other methylxanthine may be included in an over-the-counter weight loss product.


Patient selection: excessive dose of an over-the-counter weight loss product containing caffeine or other methylxanthine

 

Other sources of caffeine or methylxanthine may contribute to the total body load.

 

Clinical findings in acute toxicity:

(1) nausea and vomiting

(2) tachycardia

(3) opisthotonos

(4) myoclonic jerks

(5) seizures

(6) cerebral edema

(7) ventricular arrhythmias

(8) exertional rhabdomyolysis

 

Laboratory findings may include:

(1) hypokalemia

(2) hypocalcemia

(3) hyperglycemia

 

The methylxanthine may be only one of the components in the formulation. These other compounds (salicylate, ephredra, phenylpropanolamine, other) can also contribute to the toxic effects.


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