Criteria for Adult Onset Still's Disease (AOSD)

 

Major criteria:

(1) spiking fever with temperatures >= 39°C

(2) arthralgias

(3) transient erythema

(4) pharyngitis

(5) white blood cell differential count shows >= 80% neutrophils

(6) glycosylated ferritin <= 20%

 

Minor criteria:

(1) white blood cell count >= 10,000 per µL

(2) maculopapular rash

 

Diagnosis can be made with one of the following:

(1) >= 4 major criteria

(2) 3 major criteria and 2 minor criteria

 

In Efthimiou et al, the age of affected patients is >= 15 years.