Description

Diazepam rectal gel (marketed as Diastat AcuDial, Valeant) is a means of delivering diazepam to a pediatric patient who is having seizures and who is unable to take oral medications. The diazepam is formulated in a gel and can be absorbed across the rectal mucosa. This can stop a seizure quickly and safely if administered as directed.


 

Dosage syringes come with 10 or 20 mg of diazepam. The actual dose delivered is set at the pharmacy by dialing in the dose (in 2.5 mg increments) and then locking it.

 

Instructions:

(1) The patient should be lying down on her/is side. The clothing should be removed to expose the anus.

(2) The applicator tip is inspected for cracks before completely removing the covering cap.

(2a) Hold the syringe in one hand with the tip away from the body.

(2b) Grasp the covering cap firmly with the other hand and apply pressure to the seal pin to hold it in place.

(2c) With the first hand push the cap down a quarter of inch to view the base of the applicator tip for cracks.

(2d) Close the cap and repeat the steps on the opposite side.

(2e) If a crack is seen, do not use the syringe. Return it to the pharmacy for replacement.

(3) Check that the locked in dose matches the prescribed dose.

(4) Completely remove the cap from the syringe, removing the seal pin in the process.

(5) Lubricate the applicator tip with lubricating jelly.

(6) Bend the patient's upper leg forward to expose the anus.

(7) Separate the buttocks and identify the anus.

(8) Gently insert the syringe tip through the anus into the rectum, Insert until the rim of the syringe is in as far as it will go.

(9) Depress the syringe plunger to dispense the gel.

(10) Remove the device.

(11) Press the buttocks together.

(12) Keep the child on her/is side and observe.

(13) After the dose has been delivered, dispose of any unused gel into a sink or toilet.

(14) Discard the syringe where it cannot be reached by children; do not resuse the syringe.

 

When to call for help:

(1) The seizure continues 15 minutes after administering the gel.

(2) The seizure activity is different from the usual type.

(3) The seizures are frequent and/or severe.

(4) The patient shows abnormal breathing and/or skin color.

(5) The patient is having an unusual or serious problem.

 

An insufficient dose may be delivered if:

(1) The dose is locked at a lower than prescribed dose.

(2) There is a crack in the applicator tip.

(3) There is leakage of the gel per rectum (failure to push the buttocks together).

 

An excessive dose may be delivered if:

(1) The syringe is not locked to the prescribed dose.

(2) The syringe is locked at a higher than prescribed dose.

 


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