Adjusting the Amount of Specimen Anticoagulant for an Elevated Hematocrit


It is necessary to reduce the amount of anticoagulant (0.129 M = 3.8% sodium citrate) used in specimens for coagulation testing, when the hematocrit is elevated above the normal adult values. With higher hematocrits, less plasma is present; if not reduced, the relative amount of anticoagulant is increased and prolongs the clotting time.

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