Congestive Heart Failure | Risk Factors for Acute Renal Insufficiency Associated with Diuretic Therapy

 

Patient selection: congestive heart failure receiving diuretic therapy

 

Acute renal insufficiency was defined as a 25% increase in the serum creatinine.

 

Risk factors at baseline associated with development of acute renal insufficiency:

(1) older age (>= 68 years of age)

(2) serum sodium <= 138 mmol/L

(3) presence of systolic dysfunction

(4) high dose furosemide therapy

(5) prolonged therapy with furosemide (7 or more days)

(6) higher baseline serum creatinine (>= 1.7 mg/dL)

(7) lower mean arterial pressure (< 94 mm Hg)

 

Factors associated with a reduced risk:

(1) therapy with digoxin in a patient with systolic dysfunction