Acute Hemolysis and Disseminated Intravascular Coagulation (DIC) Following Administration of RhoGAM (Rh Immune Globulin) to an Rh-Positive Patient with Immune Thrombocytopenic Purpura (ITP)


Gaines reported acute hemolysis and disseminated intravascular coagulation (DIC) following administration of RhoGAM (immune globulin to D antigen) in a D-positive patient with immune thrombocytopenic purpura (ITP). Early detection allows for early interventions that may reduce morbidity and mortality. The author is from the Food and Drug Administration (FDA) in Rockville, Maryland,

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