Description

The Activity Score of Kahaly et al for Graves' ophthalmopathy can be used to assess response to therapy.


 

Group

Findings

Points

Subjective Symptoms

photosensitivity

1

 

lacrimation

1

 

headache

1

 

feeling of pressure behind the eyes

1

 

feeling of foreign body

1

Objective Symptoms

palpebral edema

1

 

eyelid closure

1

 

sicca syndrome

1

 

chemosis

1

 

conjunctivitis

1

 

corneal ulceration

1

 

weak convergence

2

 

blurred vision

2

 

double vision

2

 

visual acuity

2

 

restriction of visual field

2

 

proptosis according to Hertel (20/23/26/more), see below

2/4/6/8

Imaging Techniques

abnormal muscle thickness on orbit sonography

2

 

abnormal muscle thickness on orbit computed tomography

4

 

 

Proptosis According to Hertel

Grade

Points

exophthalmos <= 20 mm

0

2

exophthalmos > 21-23 mm

A

4

exophthalmos > 23-26 mm

B

6

exophthalmos > 26 mm

C

8

 

activity score =

= SUM(points for findings present)

 

Interpretation:

• minimum score: 0 points

• maximum score: 35 points

• The higher the score, the more severe the ophthalmopathy.

 

Limitations:

• The score has been criticized for giving disporportionate weight to soft tissue involvement.


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