The Activity Score of Kahaly et al for Graves' ophthalmopathy can be used to assess response to therapy.
Group |
Findings |
Points |
---|---|---|
Subjective Symptoms |
photosensitivity |
1 |
|
lacrimation |
1 |
|
headache |
1 |
|
feeling of pressure behind the eyes |
1 |
|
feeling of foreign body |
1 |
Objective Symptoms |
palpebral edema |
1 |
|
eyelid closure |
1 |
|
sicca syndrome |
1 |
|
chemosis |
1 |
|
conjunctivitis |
1 |
|
corneal ulceration |
1 |
|
weak convergence |
2 |
|
blurred vision |
2 |
|
double vision |
2 |
|
visual acuity |
2 |
|
restriction of visual field |
2 |
|
proptosis according to Hertel (20/23/26/more), see below |
2/4/6/8 |
Imaging Techniques |
abnormal muscle thickness on orbit sonography |
2 |
|
abnormal muscle thickness on orbit computed tomography |
4 |
Proptosis According to Hertel |
Grade |
Points |
---|---|---|
exophthalmos <= 20 mm |
0 |
2 |
exophthalmos > 21-23 mm |
A |
4 |
exophthalmos > 23-26 mm |
B |
6 |
exophthalmos > 26 mm |
C |
8 |
activity score =
= SUM(points for findings present)
Interpretation:
• minimum score: 0 points
• maximum score: 35 points
• The higher the score, the more severe the ophthalmopathy.
Limitations:
• The score has been criticized for giving disporportionate weight to soft tissue involvement.
Purpose: To assess the response to therapy for Graves' ophthalmopathy using the clinical activity score of Kahaly et al.
Specialty: Ophthalmology, Endocrinology
Objective: disease progression
ICD-10: E05,