The acid-base nomogram or map shows various metabolic and respiratory acid base disorders relative to a patient's pH and pCO2. The nomogram of Goldberg et al (JAMA, 1973) is commonly used.
Current Readings from Nomogram
Normal
H >= 35.50
H <= 44.70
pCO2 >= 37.00
pCO2 <= 44.00
Metabolic Acidosis
[a]
H >= -1.98855 * pCO2 + 93.11307
H <= 100
pCO2 >= 9.34
pCO2 <= 18.07
[b]
H >= -1.98855 * pCO2 + 93.11307
H <= -1.90016 * pCO2 + 115.00586
pCO2 > 18.07
pCO2 <= 26.81
[Ac]
H >= 39.8
H <= -1.90016 * pCO2 + 115.00586
pCO2 > 26.81
pCO2 < 37.00
Acute Respiratory Acidosis
H >= 0.75036 * pCO2 + 5.94429
H <= 0.77929 * pCO2 + 10.41143
pCO2 > 44.00
pCO2 <= 100.00
Chronic Respiratory Acidosis
[a]
H > 0.28482 * pCO2 + 23.66786
H < 0.76645 * pCO2 + 5.17621
pCO2 > 44.00
pCO2 <= 57.83
[b]
H > 0.28482 * pCO2 + 23.66786
H < 0.36827 * pCO2 + 28.20287
pCO2 > 57.83
pCO2 <= 100.00
Metabolic Alkalosis
[a]
H >= -0.37272 * pCO2 + 42.93068
H < 35.50
pCO2 >= 37.00
pCO2 <= 44.00
[b]
H >= -0.37272 * pCO2 + 42.93068
H < 0.36516 * pCO2 + 20.13317
pCO2 > 44.00
pCO2 < 48.19
[c]
H >= -0.37272 * pCO2 + 42.93068
H <= -0.25989 * pCO2 + 50.25395
pCO2 >= 48.19
pCO2 < 51.81
[d]
H > 0
H <= -0.25989 * pCO2 + 50.25395
pCO2 >= 51.81
pCO2 <= 62.35
Acute Respiratory Alkalosis
H >= 0.77332 * pCO2 + 6.8872
H <= 0.7068 * pCO2 + 13.64852
pCO2 >= 9.00
pCO2 < 37.00
Chronic Respiratory Alkalosis
[a]
H > 0.44379 * pCO2 + 20.70493
H < 0.13015 * pCO2 + 34.98438
pCO2 >= 9.00
pCO2 < 26.51
[b]
H > 0.69876 * pCO2 + 13.94585
H < 0.13015 * pCO2 + 34.98438
pCO2 >= 26.51
pCO2 < 37.00
Mixed Metabolic and Respiratory Acidosis
[a]
H > -1.90016 * pCO2 + 115.00586
H <= 100
pCO2 > 18.07
pCO2 < 37.00
[b]
H > 44.70
H <= 100
pCO2 >= 37.00
pCO2 <= 44.00
[c]
H > 0.77929 * pCO2 + 10.41143
H <= 100
pCO2 > 44
pCO2 < =100
Mixed Acute and Chronic Respiratory Acidosis
H < 0.75036 * pCO2 + 5.94429
H > 0.36827 * pCO2 + 28.20287
pCO2 > 57.83
pCO2 <= 100
Mixed Metabolic Alkalosis and Respiratory Acidosis
[a]
H >= -0.25989 * pCO2 + 50.25395
H < 0.28482 * pCO2 + 23.66786
pCO2 > 48.19
pCO2 <= 62.35
[b]
H >= 0
H < 0.28482 * pCO2 + 23.66786
pCO2 > 62.35
pCO2 <= 100
Mixed Respiratory and Metabolic Alkalosis
[a]
H >= 0.00
H < 0.77332 * pCO2 + 6.8872
pCO2 >= 9.00
pCO2 < 37.00
[b]
H >= 0.00
H < -0.37272 * pCO2 + 42.93068
pCO2 >= 37.00
pCO2 < 51.81
Mixed Acute and Chronic Respiratory Alkalosis
H > 0.7068 * pCO2 + 13.64852
H < 0.4438 * pCO2 + 20.70493
pCO2 >= 9.00
pCO2 < 26.51
Mixed Metabolic Acidosis and Respiratory Alkalosis
[a]
H > 0.13015 * pCO2 + 34.98438
H < -1.98855 * pCO2 + 93.11307
pCO2 >= 9.00
pCO2 < 26.81
[b]
H > 0.13015 * pCO2 + 34.98438
H < 39.8
pCO2 >= 26.81
pCO2 < 37.00
Previous Readings from Nomogram
Coordinates for Normal Range
shape of region: rectangle
corners
pH |
pCO2 |
7.35 |
37 mm Hg |
7.45 |
37 |
7.35 |
44 |
7.45 |
44 |
Coordinates for Metabolic Acidosis
shape of region: 7-sided shape
corners
pH |
pCO2 |
7.00 |
10.5 mm Hg |
7.125 |
10.5 |
7.40 |
28 |
7.00 |
18.5 |
7.095 |
18.5 |
7.355 |
37 |
7.40 |
37 |
Coordinates for Chronic Respiratory Alkalosis
shape of region: triangle
corners
pH |
pCO2 |
7.445 |
9.5 mm Hg |
7.59 |
10 |
7.405 |
37 |
Coordinates for Acute Respiratory Alkalosis
shape of region: quadrangle
corners
pH |
pCO2 |
7.64 |
9.5 |
7.8 |
11.5 |
7.41 |
37 |
7.45 |
37 |
Coordinates for Metabolic Alkalosis
shape of region: eight sided shape
corners
pH |
pCO2 |
7.40 |
44 Hg |
7.47 |
62 |
7.72 |
62 (*) |
7.77 |
52.5 (*) |
7.60 |
52.5 |
7.53 |
37 |
7.45 |
37 |
7.45 |
44 |
(*) line connecting these 2 points runs along the isobar for HCO3 = 75 mEq/L
Coordinates for Chronic Respiratory Acidosis
shape of region: quadrangle
corners
pH |
pCO2 |
7.36 |
44 Hg |
7.185 |
100 |
7.275 |
100 |
7.44 |
44 |
Coordinates for Acute Respiratory Acidosis
shape of region: parallelogram
corners
pH |
pCO2 |
7.35 |
44 mm Hg |
7.055 |
100 |
7.09 |
100 |
7.42 |
44 |
Specialty: Pulmonology, Clinical Laboratory
ICD-10: ,