Grant et al reported the simple ACE index for evaluating a patient with acute ulcerative colitis. This can help to identify a patient at risk for being a nonresponder to IV corticosteroids. The authors are from Western General Hospital, Royal Infirmary of Edinburgh, University of Edinburgh and John Radcliffe Hospital.
Patient selection: acute ulcerative colitis
Parameters on admission:
(1) serum albumin in g/L
(2) serum CRP in mg/L
(3) endoscopic severity
Parameters
Finding
Points
serum albumin
<= 30 g/L
1
> 30 g/L
0
serum CRP
< 50 mg/L
0
>= 50 mg/L
1
endoscopic severity
increased (severe, Grade 3)
1
not increased
0
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
Total Score
IV Steroid Nonresponse
0
13%
1
32%
2
46%
3
78%
Performance:
• The area under the ROC curve is 0.74.
To read more or access our algorithms and calculators, please log in or register.
