Abnormal end-diastolic flow velocity in umbilical arteries seen on Doppler ultrasonography is associated with fetal morbidity and mortality.


Pathophysiologic basis: increased vascular resistance through villous arteries



(1) intra-uterine growth retardation

(2) necrotizing enterocolitis

(3) intra-uterine fetal demise

(4) respiratory distress syndrome and/or bronchopulmonary dysplasia

(5) intraventricular hemorrhage


Indications for Doppler ultrasonography of the umbilical arteries:

(1) pre-eclampsia or eclampsia

(2) intrauterine growth restriction

(3) fetal distress


If the end-diastolic flow is significantly reduced, absent or reversed then close follow-up or expeditious delivery is indicated.


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