Prochazka et al reported a simple score for evaluating elderly patients with diffuse large B-cell lymphoma (DLBCL). The authors are from Palacky University, Charles University, Masaryk University, and University Hospital Hradec Kralove in the Czech Republic.
Patient selection: age >= 60 years with diffuse large B-cell lymphoma treated with R-CHOP
This is similar to the ABE3 score, except that it has 4 categories instead of 3.
Parameters:
(1) age (A)
(2) bulky disease (B), >= 7.5 cm in diameter
(3) ECOG performance status (E)
Parameter
Finding
Points
age
60 to 69 years
0
>= 70 years of age
1
bulky disease
no
0
yes
1
ECOG
0
0
1 to 4
1
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
• The pattern of the 3 parameters can also be used to separate patients into prognostic groups.
• The grade reflects the score (Grade I has a score of 1, Grade II 2, Grade III 3).
Age
Bulky
ECOG
Risk (Grade)
0
0
0
low (0)
1
0
0
low-intermediate (I)
0
1
0
low-intermediate (I)
0
0
1
low-intermediate (I)
1
0
1
high-intermediate (II)
0
1
1
high-intermediate (II)
1
1
0
high-intermediate (II)
1
1
1
high (III)
Risk Group
3-Year Overall Survival
low
94%
low-intermediate
77%
high-intermediate
63%
high
35%
To read more or access our algorithms and calculators, please log in or register.
