Prochazka et al reported a simple score for evaluating elderly patients with diffuse large B-cell lymphoma (DLBCL). The authors are from Palacky University, Charles University, Masaryk University, and University Hospital Hradec Kralove in the Czech Republic.
Patient selection: age >= 60 years with diffuse large B-cell lymphoma treated with R-CHOP
Parameters:
(1) age (A)
(2) bulky disease (B), >= 7.5 cm in diameter
(3) ECOG performance status (E)
Parameter
Finding
Points
age
60 to 69 years
0
>= 70 years of age
1
bulky disease
no
0
yes
1
ECOG
0
0
1 to 4
1
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
• The pattern of the 3 parameters can also be used to separate patients into prognostic groups.
Age
Bulky
ECOG
Risk
0
0
0
low
1
0
0
low
0
1
0
low
0
0
1
intermediate
1
0
1
intermediate
0
1
1
intermediate
1
1
0
high
1
1
1
high
Risk Group
3-Year Overall Survival
low
92%
intermediate
67%
high
36%
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