Pastori et al reported the 2MACE score to evaluate patients with non-valvular atrial fibrillation. This can help to identify a patient at risk for cardiovascular complications. The authors are from multiple institutions in Italy and England.
Patient selection: non-valvular atrial fibrillation
Outcome: MACE (major adverse cardiovascular events including myocardial infarction, cardiac revascularization, death)
Parameters:
(1) history of myocardial infarction or cardiac revascularization (M)
(2) metabolic syndrome (M)
(3) age in years (A)
(4) congestive heart failure (with left ventricular ejection fraction < 40%; C)
(5) thromboembolism with stroke or TIA (E)
Parameter
Finding
Points
history of myocardial infarction or revascularization
no
0
yes
1
metabolic syndrome
no
0
yes
2
age
<= 75 years
0
> 75 years
2
congestive heart failure
no
0
yes
1
thromboembolism
no
0
yes
1
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 7
• A score >= 3 is high risk for cardiovascular complications with hazard ratio of 3.9.
Performance:
• The area under the ROC curve is 0.79.
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