The American Joint Committee on Cancer (AJCC) revised its staging system for cutaneous squamous cell carcinoma in 2010.
Parameters:
(1) greatest dimension in centimeters
(2) number of risk factors
(3) invasion into orbit, maxilla, mandible and/temporal bones
(4) invasion into other bones
(5) direct perineural invasion of skull base
Risk factors:
(1) thickness > 2 mm
(2) Clark level 4 or 5 (into mid-deep reticular dermis or into subcutaneous fat)
(3) perineural invasion
(4) primary site in ear or non-hair bearing lip
(5) poorly differentiated
Greatest Dimension
Number of Risk Factors
Invasion into Specific Structures
Stage
<= 2 cm
0 or 1
none
T1
<= 2
>=2
T2
> 2 cm
NA
obit, maxilla, mandible, temporal
T3
other bone and/or direct perineural invasion of skull base
T4
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Specialty: Hematology Oncology, Surgery, general, Dermatology
