The World Health Organization (WHO) has issued criteria for the diagnosis of African trypanosomiasis.
Confirmed trypanosomiasis: presence of trypanosomes in blood, lymph node aspirates, or CSF.
Stage
Trypanosomes
CSF WBC Count
I
in blood or lymph node aspirates but not CSF
AND
<= 5 per µL
II
in CSF
OR
> 5 per µL
Recommended Therapy: based on species and Stage
T. gambiense
T rhodesiense
pentamidine
suramin
melarspoprol or eflornithine hydrochloride
melarspoprol
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Specialty: Infectious Diseases
