Description

A patient with purpura fulminans may develop limb ischemia and gangrene that requires surgical management. An algorithm used at the University of Texas Southwestern can be used to preserve as much tissue and function as possible.


 

Step 1: Is there evidence of a compartment syndrome?

(1) Diagnostic tests may include direct measurement of compartment pressure or MRI.

(2) Patients with evidence of a compartment syndrome should undergo fasciotomy.

 

Step 2 - Support and stabilize patient:

(1) Observe and provide hemodynamic support.

(2) Provide silvadene dressing changes to involved regions BID.

 

Step 3 - Tissue management:

(1) Perform serial debridements in the operating room.

(2) Preserve all questionable tissue for a second look. This helps maximize soft tissue available for reconstruction.

(3) Assess tissue requirements.

 

Step 4 - Perform definitive surgeries once demarcation complete:

(1) Avoid amputation whenever useful function of an affected limb can be preserved.

(2) Maximize the length on gangrenous limbs. Any tibial length should be preserved in a growing child.

(3) Spare joints whenever possible.

(4) Cover vascularized areas with skin grafts.

(5) Cover exposed bone and joints with microvascular free tissue transfer.

 


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