Small Fiber Neuropathy Diagnosis | Medical Algorithm

Are you evaluating a patient for evidence of small fiber neuropathy?

Yes

Does the patient have?

• problems detecting a pinprick?

Yes

• thermal sensory loss?

Yes

• allodynia?

Yes

• hyperalgesia?

Yes

• an abnormal thermal threshold (warming or cooling) at the foot by quantitative sensory testing?

Yes

• decreased intra-epidermal nerve fiber (IEFN) density in a skin biopsy from the lower leg?

Yes

• absent deep tendon reflexes (DTR)?

Yes

• proprioceptive sensory loss?

Yes

• vibratory sensory loss?

Yes

• sensory loss to light touch?

Yes

• any signs of motor fiber impairment?

Yes

• any abnormality on sensorimotor nerve conduction study (NCS)?

Yes

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Specialty

Objective

ICD-10

Criteria for Small Fibre (Fiber) Neuropathy (SFN)

Purpose: To evaluate a patient for clinical findings associated with small fiber neuropathy (SFN) based on the criteria of Devigili et al.