Populations with a low salt intake tend to have lower blood pressures than populations with high salt intake. Salt sensitivity or resistance is based on the premise that salt intake can affect an individual patient's blood pressure.
Endpoint: change in mean arterial blood pressure (MAP)
decrease in MAP >= 3 mm Hg with sodium restriction
Franco and Oparil
decrease in MAP >= 10 mm Hg with sodium and volume restriction
Campese
increase in MAP >= 10 mm Hg with high sodium intake
Clinical studies on salt sensitivity have been inconsistent, with significant inter- and intra-individual variability.
In clinical practice there may be a noticeable correlation between sodium intake and blood pressure control. Some patients with poorly controlled blood pressure may improve significantly if placed on sodium restriction.
In general restriction of sodium intake is beneficial for many patients and is recommended.
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