Description

Wang et al developed a score for predicting the risk of stroke or death within 5 years for a patient with new-onset atrial fibrillation. This can help identify those patients who may benefit from interventions. The authors are from the Framingham Heart Study and most are from Boston.


 

NOTES:

(1) The concurrent point score for predicting risk of stroke alone is in 17.10.14.

 

Parameters:

(1) age

(2) systolic blood pressure (based on the mean of 2 physician measurements)

(3) diabetes mellitus (fasting glucose >= 140 mg/dL; a random glucose >= 200 mg/dL; use of insulin or a hypoglycemic agent)

(4) cigarette smoker (smoked cigarettes within past year)

(5) prior history of myocardial infarct or congestive heart failure

(6) murmur

(7) left ventricular hypertrophy on ECG

 

Parameter

Finding

Points

age in years

55 years

0

 

56 years

1

 

57 years

2

 

58 or 59 years

3

 

60 years

4

 

61 years

5

 

62 years

6

 

63 years

7

 

64 or 65 years

8

 

66 years

9

 

67 years

10

 

68 years

11

 

69 years

12

 

70 or 71 years

13

 

72 years

14

 

73 years

15

 

74 years

16

 

75 years

17

 

76 or 77 years

18

 

78 years

19

 

79 years

20

 

80 years

21

 

81 years

22

 

82 or 83 years

23

 

84 years

24

 

85 years

25

 

86 years

26

 

87 years

27

 

88 years

28

 

89 years

29

 

90 or 91 years

30

 

92 years

31

 

93 years

32

 

94 years

33

systolic blood pressure

< 120 mm Hg

0

 

120 - 139 mm Hg

1

 

140 - 159 mm Hg

2

 

160 - 179 mm Hg

3

 

>= 180 mm Hg

5

diabetes mellitus

no

0

 

yes

4

smoker

no

0

 

yes

5

previous history of MI or CHF

no

0

 

yes

6

murmur

no

0

 

yes

4

LVH on ECG

no

0

 

yes

2

 

total score =

= SUM(points for all 7 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 59

• The higher the score the greater the risk of stroke or death within 5 years.

 

Total Score

5 Year Risk of Stroke

0

8%

1

9%

2 or 3

10%

4

11%

5

12%

6

13%

7

15%

8

16%

9

17%

10

19%

11

20%

12

22%

13

24%

14

26%

15

28%

16

30%

17

32%

18

35%

19

37%

20

40%

21

43%

22

46%

23

49%

24

52%

25

55%

26

58%

27

61%

28

66%

29

68%

30

71%

31

75%

32

78%

>= 33

> 80%

 

If this data is entered into JMP, the following third order equation is derived:

 

risk of stroke or death in 5 years as a percent (from 0 to 100) =

= (-0.000539 * ((points)^3)) + (0.0761999 * ((points)^2)) + (0.272659 * (points)) + 8.7380027


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