Description

Surgery is associated with an increased risk of deep venous thrombosis and pulmonary embolism. Identification of patients at risk allows for prophylaxis and early diagnosis.


 

Type of Surgery

Age of Patient

Other Risk Factors

Risk Group

uncomplicated minor

<= 40

none

very low

major

<= 40

none

low

major

<= 40

1 risk factor

moderate

uncomplicated minor

> 40

none

low

major

> 40

none

moderate

major

> 40

1 risk factor

high

major

> 40

previous venous thromboembolus or significant malignant disease or > 1 risk factor

very high

 

Risk factors for venous thrombosis (used as headers in table):

(1) age

(2) major surgery, major orthopedic surgery, or trauma with fracture of pelvis, hip and/or leg

(3) history of previous venous thromboembolus

(4) significant malignant disease

 

Additional risk factors:

(5) prolonged immobilization

(6) paralysis

(7) obesity

(8) atrial fibrillation

(9) heart failure

(10) myocardial infarction

(11) stroke

(12) hyperhomocysteinemia

(13) oral contraceptives or hormone replacement therapy

(14) inherited hypercoagulable disorders (defects in antithrombin III, protein S, protein C, factor V Leiden, etc.)

(15) acquired hypercoagulable disorders: anticardiolipin antibodies, lupus anticoagulants, polycythemia rubra vera, myeloproliferative disorder, hyperviscosity syndrome

 

Risk Group

Prophylaxis to Prevent Pulmonary Embolism

very low and low

early ambulation

moderate

elastic stockings, low dose unfractionated heparin, or intermittent pneumatic compression

high

low dose unfractionated heparin, or low molecular weight heparin, or (intermittent pneumatic compression + elastic stockings)

very high

intermittent pneumatic compression AND (low dose unfractionated heparin or low molecular weight heparin or adjusted dose warfarin)

 


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