A patient with systemic lupus erythematosus (SLE) may be at increased risk for thrombosis if certain risk factors are present. A patient identified as being at increased risk may benefit from prophylactic therapy.
Risk factors of Tektonidou et al for a patient with antiphospholipid antibodies:
(1) male gender
(2) presence of lupus anticoagulant
(3) consistently positive anticardiolipin antibodies (NOT negative NOR intermittently positive)
Risk factors of Tektonidou et al for a patient without antiphospholipid antibodies:
(1) male gender
(2) hypertension
The risk factors of Tarr et al are similar but included:
(1) a history of thrombosis
(2) presence of all 3 of the following: lupus anticoagulant, antiphospholipid antibodies, anticardiolipin antibodies
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