Description

Queenan offered a method of assessing severity of hemolytic disease of the newborn based on amniotic fluid bilirubin.


 

Measurement on amniotic fluid: delta OD450

 

Upper Boundary Line for < 28 Weeks Gestation

 

y = 0.24

 

LOG10 [100 * (delta OD450)] = 0.24

 

Upper Boundary Line for 28 - 40 Weeks Gestation

 

week 28: y = 0.24

week 40: y = 0.133

slope = - 0.020

 

LOG10(100 * (delta OD450)) = ((-0.020) * (week gestation)) + 1.91

 

Lower Boundary Line

 

week 20: y = 0.126

week 40: y = 0.05

slope = -0.020

 

LOG10(100 * (delta OD450)) = ((- 0.020) * (week gestation)) + 1.5

Location

Interpretation

above upper boundary

intrauterine or neonatal death possible

within zone

area of overlap

below lower boundary

infant survives

 


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