Patient selection: male with PUV detected in utero
Outcome: chronic renal failure
Factors associated with adverse outcome:
(1) oligohydramnios (relative risk 11)
(2) need for ventilatory support (relative risk 6)
(3) initial serum urea (? urea nitrogen) >= 40 mg/dL (relative risk 4)
(4) bilateral vesicoureteral reflux (VUR, relative risk 6)
where:
• The authors state the unilateral VUR was protective but the relative risk is 0.92.
• An initial serum creatinine >= 0.8 mg/dL was also associated with risk. This might be a bit more reliable to track than urea.
• The timing of initial laboratory tests relative to relief of obstruction was not stated. Other studies have shown that evidence of renal damage after initial surgery is associated with progression.
