Description

The prognosis in patients being evaluated preoperatively for coronary artery bypass surgery can be estimated using a clinical severity score using 13 clinical and laboratory factors.


Preoperative factors evaluated:

(1) age

(2) body weight

(3) emergency need for surgery

(4) history of previous vascular surgery

(5) history of previous heart surgery

(6) history of previous cardiovascular disease

(7) history of chronic obstructive lung disease

(8) history of diabetes mellitus requiring oral drug or insulin therapy

(9) aortic stenosis

(10) mitral insufficiency

(11) severe left ventricular dysfunction

(12) hematocrit

(13) serum creatinine

 

Preoperative Factor

Finding

Points

serum creatinine

< 1.6

0

 

>= 1.6 to <= 1.8 mg/dL

1

 

>= 1.9 mg/dL

4

emergency case

yes

6

 

no

0

reoperation

yes

3

 

no

0

severe left ventricular dysfunction

present

3

 

absent

0

operative mitral valve insufficiency

present

3

 

absent

0

age

< 65

0

 

>= 65 and <= 74

1

 

>= 75

2

prior vascular surgery

present

2

 

absent

0

chronic obstructive lung disease with use of bronchodilating drugs

present

2

 

absent

0

anemia (hematocrit <= 34%)

hematocrit <= 34%

2

 

hematocrit > 34%

0

aortic valve stenosis, operated

present

1

 

absent

0

body weight <= 65 kilograms

<= 65 kilograms

1

 

> 65 kilograms

0

diabetes, on oral agent or insulin therapy

present

1

 

absent

0

cerebrovascular disease

present

1

 

absent

0

 

where:

• An emergency case defined as unstable angina, unstable hemodynamics or ischemic valvular dysfunction that could not be controlled medically, complications of percutaneous transluminal angioplasty or complications of cardiac catheterization.

• Reoperation indicates previous surgery on the heart.

• Severe left ventricular dysfunction is associated with an ejection fraction of < 35%.

• Prior vascular surgery includes carotid endarterectomy or heart valve replacement.

• "Aortic valve stenosis, operated" is not described further. I will take it has being a history of surgery for aortic stenosis.

 

clinical severity score =

= SUM(points for 13 preoperative factors)

 

Interpretation:

• minimum score: 0

• maximum score: 31

 

Severity Score

Morbidity

Mortality

0

3%

< 1%

1

4%

1%

2

6%

2%

3

10%

2%

4

12%

2%

5

11%

3%

6

18%

4%

7 - 9

23%

7%

>= 10

50%

27%

estimated from Figures 1 and 2 pages 2346-2347

 

Morbidity included one or more of the following:

(1) cardiac complications

(2) need for mechanical ventilation

(3) central nervous system complication

(4) oliguric or anuric renal failure

(5) serious infection

(6) death

 

Mortality included:

(1) death during hospitalization for surgery, regardless of length of stay

(2) death within 30 days of hospital discharge

 

Logistic Regression Analysis

 

The authors developed the clinical severity score from logistic regression analysis for morbidity and mortality associated preoperative factors.

 

Factor

Coefficient for Morbidity

Coefficient for Mortality

emergency case

2.198

2.020

serum creatinine >= 1.9 mg/dL

1.043

1.306

reoperation

0.894

1.066

severe left ventricular dysfunction

0.727

1.334

mitral valve insufficiency

0.953

0.929

age per decade

0.374

0.662

diabetes on medication

0.388

 

weight <= 65 kilograms

0.374

 

anemia with hematocrit < 34%

0.449

0.987

COPD on medication

0.387

0.872

cerebrovascular disease

0.339

 

aortic stenosis, operated

0.401

 

prior vascular surgery

0.340

0.918

constant

-5.073

-9.216

from Table 2 page 2346


To read more or access our algorithms and calculators, please log in or register.