Sedrine et al developed the Osteoporosis Index of Risk (OSIRIS) to identify postmenopausal women at risk for having a low bone mineral density. The authors are from the WHO Collaborating Center for Public Health Aspects of Rheumatic Disease in Liege, Belgium.
NOTE: OSIRIS is a registered trademark.
Parameters:
(1) age in years
(2) body weight in kilograms
(3) history of a low impact fracture
(4) current hormone replacement therapy (HRT)
Parameter |
Findings |
Points |
history of low impact fracture |
no |
0 |
|
yes |
-2 |
current hormone replacement therapy |
no |
0 |
|
yes |
+2 |
OSIRIS =
= INT(-2 * (age in years)/10) + INT(2 * (body weight in kg)/10) + (points for fracture history) + (points for current HRT)
where:
• For age in years and body weight the values were multiplied by a factor and then the right-most digit is removed. This is because units were based on 10 years and 10 kilograms respectively.
Interpretation:
• minimum score: -8
• maximum score: +12
OSIRIS |
Risk of Low Bone Mineral Density |
Percent Women with T Score < -2.5 |
> 1 |
low risk |
7% |
-3 to 1 |
intermediate risk |
39% |
< - 3 |
high risk |
66% |
Specialty: Surgery, orthopedic, Endocrinology, Nutrition
ICD-10: ,