Cheng et al developed risk table for patients with ST-elevation myocardial infarction (STEMI) and cardiogenic shock. This can help to identify a patient who may benefit from more aggressive management. The authors are from Erasmus Medical Center in Rotterdam.
Patient selection: STEMI with cardiogenic shock undergoing PCI
Outcome: 30-day mortality
Parameters available at time of admission:
(1) serum creatinine relative to upper limit of normal for gender
(2) serum lactate in mmol/L
(3) age in years
Upper limit of serum creatinine for males: 115 µmol/L
Upper limit of serum creatinine for females: 90 µmol/L
Creatinine |
Lactate |
Age |
percent |
---|---|---|---|
<= ULN |
< 1.7 |
< 55 years |
8 |
|
|
55 to 64 |
12 |
|
|
65 to 75 |
19 |
|
|
> 75 years |
26 |
|
1.7 to 5.0 |
< 55 years |
14 |
|
|
55 to 64 |
21 |
|
|
65 to 75 |
31 |
|
|
> 75 years |
43 |
|
5.1 to 8.5 |
< 55 years |
24 |
|
|
55 to 64 |
34 |
|
|
65 to 75 |
46 |
|
|
> 75 years |
49 |
|
> 8.5 |
< 55 years |
37 |
|
|
55 to 64 |
50 |
|
|
65 to 75 |
62 |
|
|
> 75 years |
73 |
> ULN |
< 1.7 |
< 55 years |
19 |
|
|
55 to 64 |
29 |
|
|
65 to 75 |
40 |
|
|
> 75 years |
53 |
|
1.7 to 5.0 |
< 55 years |
32 |
|
|
55 to 64 |
44 |
|
|
65 to 75 |
56 |
|
|
> 75 years |
68 |
|
5.1 to 8.5 |
< 55 years |
47 |
|
|
55 to 64 |
60 |
|
|
65 to 75 |
71 |
|
|
> 75 years |
81 |
|
> 8.5 |
< 55 years |
63 |
|
|
55 to 64 |
74 |
|
|
65 to 75 |
83 |
|
|
> 75 years |
89 |
where:
• The breakpoints have issues. There was no coverage for creatinine equal to ULN. Lactate overlaps at 5.1. Ages overlap at 65.
Performance:
• The area under the ROC curve was 0.75.
Specialty: Cardiology
ICD-10: ,