Abrey et al developed a prognostic model for evaluating patients with primary central nervous system (CNS) lymphoma. This can help identify patients who may require more aggressive management. The authors are from Memorial Sloan-Kettering Cancer Center in New York City.
Parameters:
(1) age in years
(2) Karnofsky performance score (KPS)
Age of the Patient
Karnofsky PS
Prognostic Class
<= 50 years
NA
1
> 50 years
>= 70
2
> 50 years
< 70
3
where:
• A KPS of 70 indicates a person who is unable to work but who can take care of self. Lower scores indicate increasing dependence on others.
Prognostic Class
Prognosis
Median Overall Survival (MKSCC patients)
1
fair
8.5 years
2
guarded
3.2 years
3
poor
1.1 years
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