Onder et al reported the GerontoNet ADR risk score for estimating the risk of adverse drug reactions (ADR) in a hospitalized geriatric patient. The authors are from multiple institutions in Europe and the data analyzed was from GIFA (Gruppo Italiano di Farmacoepidemiologie nell'Anziano).
Parameters:
(1) number of comorbid conditions
(2) heart failure
(3) liver failure
(4) renal failure
(5) history of an adverse drug reaction (ADR)
(6) number of drugs
|
Parameter |
Finding |
Points |
|
number of comorbid conditions |
0 to 3 |
0 |
|
|
>= 4 |
1 |
|
heart failure |
absent |
0 |
|
|
present |
1 |
|
liver failure |
absent |
0 |
|
|
present |
1 |
|
renal failure |
absent |
0 |
|
|
present (GFR < 60 mL/min) |
1 |
|
history of ADR |
absent |
0 |
|
|
present |
2 |
|
number of drugs |
1 to 4 |
0 |
|
|
5 to 7 |
1 |
|
|
>= 8 |
4 |
ADR risk score =
= SUM(points for all 6 parameters)
Interpretation:
• minimum score: 0
• maximum score: 10
• The higher the score the greater the risk of having an adverse drug reaction.
|
ADR Risk Score |
Percent with ADR |
|
0 or 1 |
2 to 4% |
|
2 or 3 |
4% |
|
4 or 5 |
8 to 10% |
|
6 or 7 |
12% |
|
8 to 10 |
22 to 28% |
Purpose: To identify a geriatric patient in the hospital who is at risk for an adverse drug reaction (ADR) using the GerontoNet ADR risk score.
Specialty: Toxicology, Emergency Medicine, Critical Care
Objective: risk factors, adverse effects
ICD-10: T78, T88.7, Y40-Y59, Y70-Y82,
