Factors of Rabbat et al Associated with Survival in a Patient with Acute Myeloid Leukemia (AML) Admitted to the Intensive Care Unit (ICU)

 

Outcomes:

(1) survival to ICU discharge

(2) survival at 1 year after discharge

 

NOTE: A patient with a very high risk of death would not be admitted to the ICU (see previous section).

 

Factors associated with ICU survival:

(1) low to intermediate SAPS II score within 24 hours of ICU admission (see 30.11.02; mean for survivors was 43 with standard deviation 16; mean for nonsurvivors 79 with standard deviation 27)

(2) not using invasive mechanical ventilation (either absence of respiratory failure or use of noninvasive ventilation)

 

Number of Risk Factors Present	Mortality Rate
0	0%
1	38%
2	73%

 

Factors associated with survival at 1 year if discharged from ICU alive:

(1) achievement of complete remission

(2) AML Type 3 (FAB classification, promyelocytic)

(3) age <= 60 years

(4) ECOG performance status 0 or 1

 

In multivariate analysis only the achievement of complete remission was an independent predictor for 1 year survival.