Brizuela Sanz et al developed the ERICVA model for critical limb ischemia. The complete model uses 11 parameters while a simplified version uses 5. The authors are from Hospital Clinica Universitario, University of Vallalodid in Spain.
ERICVA is derived from Escala de Riesgo en Isquemia Critica de Valladolid
Patient selection: critical limb ischemia, Rutherford class 4 to 6
Parameters:
(1) dialysis
(2) active cancer within the past 5 years
(3) hematocrit in percent
(4) neutrophil to lymphocyte ratio
(5) Rutherford class
(6) cerebrovascular disease
(7) previous contralateral major amputation
(8) diabetes mellitus
(9) COPD or asthma
(10) peri-malleolar Doppler signal
(11) admission
neutrophil to lymphocyte ratio =
= (absolute neutrophil count per µL) / (absolute lymphocyte count per µL)
Parameter |
Finding |
Points |
dialysis |
no |
0 |
|
yes |
9 |
active cancer |
no |
0 |
|
yes |
12 |
hematocrit |
>= 30% |
0 |
|
< 30% |
9 |
neutrophil to lymphocyte ratio |
<= 5 |
0 |
|
> 5 |
8 |
Rutherford class |
4 or 5 |
0 |
|
6 |
9 |
cerebrovascular disease |
absent |
0 |
|
present |
5 |
previous contralateral major amputation |
no |
0 |
|
yes |
5 |
diabetes mellitus |
absent |
0 |
|
present |
3 |
COPD or asthma |
absent |
0 |
|
present |
6 |
peri-malleolar Doppler signal |
present |
0 |
|
absent |
6 |
admission |
urgent |
3 |
|
not urgent |
0 |
total score =
= SUM(points for all 11 parameters)
Interpretation:
• minimum score: 0
• maximum score: 75
• The higher the score the greater the risk.
Total Score |
Risk Level |
5-Year Survival |
0-9 |
low |
67% |
10-19 |
medium |
45% |
>= 20 |
high |
18% |
Performance:
• The area under the ROC curve was 0.74 for the development set and 0.71 for the validation set.
Specialty: Cardiology