medical decision support medical decision support
Sign In

Dutch-English LEMS Tumor Association Prediction (DELTA-P) Score for Identifying a Patient with Lambert-Eaton Myasthenic Syndrome Due to a Small Cell Lung Cancer (SCLC)

Purpose: To determine if a patient with the Lambert-Eaton Myasthenic Syndrome (LEMS) should be screened for small cell lung cancer based on the DELTA-P score.

Description

Titulaer et al reported a score for use in patients with the Lambert-Eaton Myasthenic Syndrome (LEMS). This can help to identify a patient who should be evaluated for small cell undifferentiated lung carcinoma. The authors are from the Dutch-English Lambert-Eaton Myasthenic Syndrome Tumor Association.


Patient selection: Lambert-Eaton Myasthenia Syndrome (LEMS)

 

Parameters:

(1) dysarthria, dysphagia, muscle weakness (D)

(2) erectile dysfunction (E)

(3) loss of weight (L)

(4) tobacco use at onset (T)

(5) age at onet (A)

(6) performance on the Karnofsky Performance Scale or KPS (P)

 

Parameter

Finding

Points

dysarthria, dysphagia, neck weakness, bulbar weakness, difficulty chewing

absent

0

 

present

1

male with erectile dysfunction

absent

0

 

present

1

weight loss

< 5%

0

 

>= 5%

1

using tobacco at onset

no

0

 

yes

1

age at onset

< 50 years of age

0

 

>= 50 years of age

1

performance on KPS

70 to 100

0

 

10 to 60

1

 

total DELTA-P score =

= SUM(points for all 6 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 6

• The higher the score the greater the risk of the patient having a small cell lung cancer.

 

Total DELTA-P

Percent with Small Cell Lung Cancer

0

0%

1

2.6%

2

29%

3

84%

4

94%

5

97%

6

100%

 


To read more or access our algorithms and calculators, please log in or register.

Specialty

Objective

ICD-10