McLeod et al identified inappropriate prescription practices for older adults in Canada. Certain prescriptions should be avoided in patients with cardiovascular disease. The authors are from McGill University in Montreal.
Disorder
Drug
Comorbid
Reason
hypertension
beta-adrenergic blocker
asthma or COPD
worsen asthma or COPD
angina
beta-adrenergic blocker
asthma, COPD, heart failure
worsen asthma, COPD or heart failure
hypertension
reserpine
depression and extrapyramidal effects
atrial fibrillation
disopyramide
anticholinergic side effects, sudden death
hypertension
thiazide
gout
worsen gout
hypertension
calcium channel blocker
heart failure
worsen heart failure
hypertension
beta-adrenergic blocker
heart failure
worsen heart failure
angina
beta-adrenergic blocker, long term
Raynaud
worsen Raynaud
hypertension
beta-adrenergic blocker, long term
Raynaud
worsen Raynaud
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