The demonstration of dissemination in CNS lesions on MRI scans over time is one criteria for the diagnosis of multiple sclerosis.
Dissemination in time is said to be present if one of the following is identified on MRI.
Timing of MRI
MRI Finding
first scan < 3 months after onset, and
second scan done >= 3 months after onset
new gadolinium-enhancing lesion
second scan done >= 3 months after onset, and third scan done >=3 months after first scan (and after second)
new T2 or gadolinium-enhancing lesion
first scan done >=3 months after onset
gadolinium-enhancing lesion in a site not implicated in the original event
first scan done >=3 months after onset, and second scan done later (usually 3 months)
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Specialty: Neurology, Immunology/Rheumatology
ICD-10: ,