Description

Wildman et al developed an score to measure the physiologic derangement associated with an acute exacerbation of COPD and/or asthma. The authors are from Northern General Hospital Sheffield, Intensive Care National Audit & Research Centre London, and the London School of Hygiene and Tropical Medicine.


 

Patient selection: exacerbation of an obstructive airways disease (COPD, asthma, both)

 

Parameters:

(1) heart rate in beats per minute

(2) mean arterial pressure (MAP) in mm Hg

(3) arterial pH

(4) serum sodium in mmol/L

(5) blood urea in mmol/L

(6) serum creatinine in µmol/L

(7) serum albumin in g/L

(8) white blood cell count in 10^9/L

 

Parameter

Finding

Points

heart rate

< 80

3

 

80 to 109

0

 

110 to 129

2

 

130 to 149

3

 

150 to 169

5

 

>= 170

7

MAP

< 40

19

 

40 to 49

12

 

50 to 59

9

 

60 to 69

6

 

70 to 89

3

 

90 to 99

0

 

>= 100

4

pH

< 7.00

9

 

7.00 to 7.09

6

 

7.10 to 7.19

3

 

7.20 to 7.24

1

 

>= 7.25

0

serum sodium

< 130

6

 

130 to 134

2

 

135 to 144

0

 

>= 145

2

blood urea

< 2.5

0

 

2.5 to 6.7

8

 

6.8 to 11.9

16

 

12 to 17.9

22

 

>= 18.0

24

serum creatinine

< 150

0

 

150 to 199

5

 

>= 200

8

serum albumin

< 15

20

 

15 to 19.9

14

 

20 to 24.9

8

 

25 to 29.9

6

 

30 to 34.9

4

 

>= 35

0

WBC count

< 4

7

 

4 to 14.9

0

 

15 to 19.9

1

 

20 to 24.9

4

 

>= 25

7

 

total CAPS =

= SUM(points for all 8 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 100

• The higher the score the worse the overall survival.

 

X =

= (0.07530 * (score)) - 3.367

 

probability of mortality =

= 1 / (1 + EXP((-1) * X))

 


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