The chemical name for GBL is 2(3H)-dihydrofuranone.
GBL and 1,4-BD are metabolized to GHB by peripheral lactonases, alcohol dehydrogenase and aldehyde dehydrogenase.
GHB, GBL and 1,4-BD:
(1) inhibit GABA receptors in the central nervous system
(2) increase dopamine synthesis by stimulating tyrosine hydroxylase
Desired acute effects include:
(1) sedation with central nervous system depression
(2) euphoria
(3) heightened sexuality
Unintended acute effects:
(1) respiratory depression
(2) bradycardia
(3) involuntary movements
(4) loss of consciousness
(5) death
Chronic effects:
(1) withdrawal reaction on sudden discontinuation
(2) anxiety and/or depression
(3) tremor
(4) insomnia
(5) Wernicke-Korsakoff syndrome
Additional concerns:
(1) Industrial grade chemicals may be impure and contain toxic chemicals.
(2) People who attend clubs may be abusing alcohol or other drugs.
(3) Body builders may also be abusing anabolic steroids.
