Kahaly et al used a clinical activity score to monitor patients with acromegaly. This can be used to monitor a patient over time and to evaluate the response to therapy. The authors are from Johannes Gutenberg University Hospital in Mainz, Germany.
Subjective parameters:
(1) headache
(2) arthralgias
(3) hyperhidrosis
(4) paresthesias
Subjective parameters for males:
(5) impotence
Subjective parameters for females:
(5) menstrual abnormalities
(6) galactorrhea
Objective parameters:
(1) macroglossia
(2) acral (extremity) enlargement
(3) thyroid goiter
(4) voice changes
(5) carpal tunnel syndrome
(6) visual disturbances
(7) hypertension
(8) diabetes mellitus
(9) ring size for the fourth finger
(10) shoe size
Change
Points
not abnormal
0
mild
1
moderate
2
severity
3
total score =
= SUM(points for all subjective and objective parameters)
Interpretation:
• minimum score: 0
• maximum score for males: 45
• maximum score for females: 48
• The higher the score the more severe the acromegaly.
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