Description

Emancipator classified the histopathologic changes seen in IgA nephropathy and Henoch-Schonlein nephritis.


 

Requirement for the renal biopsy: 9 or more glomeruli

 

Parameters:

(1) glomerular changes other than crescents

(2) crescents

 

Glomerular Changes Other Than Crescents

Glomeruli with Crescents

Class

none

none

0

minimal

none

I

mesangial proliferation without extracapillary proliferation

none

II

mesangial proliferation with extracapillary proliferation

< 50%

III

mesangial proliferation with extracapillary proliferation

50-75%

IV

mesangial proliferation with extracapillary proliferation

> 75% of glomeruli

V

pseudomembranoproliferative glomerulonephritis

NA

VI

 

where:

• Classes II to V may or may not show endocapillary proliferation.

 


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