The Centers for Disease Control and Prevention (CDC) developed a number of algorithms for the management of a neonate depending on the risk for Group B Streptococcal infection (GBS).
Parameters:
(1) signs of neonatal sepsis
(2) maternal chorioamnionitis
(3) indications for GBS prophylaxis
(4) adequacy of prophylaxis
(5) features of pregnancy
Neonatal Sepsis |
Chorio-amnionitis |
GBS Prophylax |
Adequate Prophylax |
Pregnancy Features |
Step |
---|---|---|---|---|---|
Y |
NA |
NA |
NA |
NA |
1 |
N |
Y |
NA |
NA |
NA |
2 |
N |
N |
N |
NA |
NA |
3 |
N |
N |
Y |
Y |
NA |
4 |
N |
N |
Y |
N |
see below |
5 |
N |
N |
Y |
N |
see below |
6 |
Step 5: >= 37 weeks gestation AND membrane rupture < 18 hours
Step 6: < 37 weeks gestation OR membrane rupture >= 18 hours
Step |
Management |
---|---|
1 |
Full sepsis workup and start antibiotic therapy. |
2 |
Limited workup and start antibiotic therapy. |
3 |
Routine clinical care. |
4 |
Observe for >= 48 hours. Workup and treat if septic. |
5 |
Observe for >= 48 hours. Workup and treat if septic |
6 |
Limited workup. Observe for >= 48 hours. Treat if septic. |
Purpose: To manage a newborn who may have been exposed to Group B Streptococcus (GBS) using the 2010 CDC guidelines.
Specialty: Infectious Diseases, Pharmacology, clinical, Obstetrics & Gynecology, Pedatrics
Objective: risk factors, complications, selection, complication detection
ICD-10: A40.1,