Litvan et al identified clinical features that can help distinguish progressive supranuclear palsy (PSP) from diffuse Lewy body disease (DLBD). The authors are from NIH, Massachusetts General Hospital, Hopital de la Salpetriere (Paris), Ludwig Boltzmann Institute of Clinical Neurobiology (Vienna) and the Institute of Neurology (London).
Analysis: both logistic regression and CART performed
Parameters:
(1) supranuclear (SN) vertical gaze palsy
(2) gait instability
(3) delusions
SN Vertical Gaze Palsy
Gait Instability
Delusions
Diagnosis
present
NA
NA
probable PSP (rare DLBD)
absent
absent
NA
DLBD
absent
present
absent
probable PSP (possible DLBD)
absent
present
present
DLBD
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