Description

Each treatment strategy has potential risks and benefits. The treatment threshold uses a treatment's benefit and risk when used for a given condition to help decide if and when to treat.


 

benefit for treatment =

= (risk of adverse outcome from the disease in those untreated) - (risk of adverse outcome from the disease with treatment)

 

risk of treatment =

= (risk of significant adverse complication due to treatment)

 

benefit-to-risk ratio =

= (benefit for treatment) / (risk for treatment)

 

treatment threshold =

= 1 / ((benefit-to-risk ratio) +1 ) =

= (risk) / ((benefit) + (risk))

 

Interpretation:

• Treatment should be given when the risk of having the condition exceeds the treatment threshold.

• Treatment should be withheld if the risk of having the condition is less than the treatment threshold.

 


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