Abnormal end-diastolic flow velocity in umbilical arteries seen on Doppler ultrasonography is associated with fetal morbidity and mortality.
Pathophysiologic basis: increased vascular resistance through villous arteries
Associations:
(1) intra-uterine growth retardation
(2) necrotizing enterocolitis
(3) intra-uterine fetal demise
(4) respiratory distress syndrome and/or bronchopulmonary dysplasia
(5) intraventricular hemorrhage
Indications for Doppler ultrasonography of the umbilical arteries:
(1) pre-eclampsia or eclampsia
(2) intrauterine growth restriction
(3) fetal distress
If the end-diastolic flow is significantly reduced, absent or reversed then close follow-up or expeditious delivery is indicated.
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Specialty: Obstetrics & Gynecology, Pedatrics
