The Michigan Diabetic Neuropathy Score (MDNS) can be used to evaluate a patient with diabetes mellitus for peripheral neuropathy. It can used in conjunction with screening tests such as the Michigan Neuropathy Screening Instrument (MNSI) to confirm the presence of a neuropathy. The score can be monitored over time to evaluate disease progression.
Clinical examination:
(1) sensory: vibration in great toe, touch with 10 gram filament, pin prick to great toe
(2) muscle strength: finger spread, great toe extension, ankle dorsiflexion
(3) reflex testing: biceps brachii, triceps brachii, quadriceps femoris, Achilles
Nerve conduction studies:
(1) sural nerve
(2) peroneal motor
(3) median sensory nerve
(4) median motor nerve
(5) ulnar sensory nerve
Clinical Examination Test |
Finding |
Points |
---|---|---|
vibration in right great toe |
normal |
0 |
|
decreased |
1 |
|
absent |
2 |
vibration in left great toe |
normal |
0 |
|
decreased |
1 |
|
absent |
2 |
10 gram filament test to right great toe |
normal (8-10 of 10) |
0 |
|
decreased (1-7 of 10) |
1 |
|
absent (0 of 10) |
2 |
10 gram filament test to left great toe |
normal (8-10 of 10) |
0 |
|
decreased (1-7 of 10) |
1 |
|
absent (0 of 10) |
2 |
pin prick to dorsum of right great toe |
painful |
0 |
|
not painful |
2 |
pin prick to dorsum of left great toe |
painful |
0 |
|
not painful |
2 |
right hand finger spread muscle strength |
normal |
0 |
|
mild to moderate |
1 |
|
severe |
2 |
|
absent |
3 |
left hand finger spread muscle strength |
normal |
0 |
|
mild to moderate |
1 |
|
severe |
2 |
|
absent |
3 |
right great toe extension muscle strength |
normal |
0 |
|
mild to moderate |
1 |
|
severe |
2 |
|
absent |
3 |
left great toe extension muscle strength |
normal |
0 |
|
mild to moderate |
1 |
|
severe |
2 |
|
absent |
3 |
right ankle dorsiflexion muscle strength |
normal |
0 |
|
mild to moderate |
1 |
|
severe |
2 |
|
absent |
3 |
left ankle dorsiflexion muscle strength |
normal |
0 |
|
mild to moderate |
1 |
|
severe |
2 |
|
absent |
3 |
right biceps brachii reflex |
present |
0 |
|
present with reinforcement |
1 |
|
absent |
2 |
left biceps brachii reflex |
present |
0 |
|
present with reinforcement |
1 |
|
absent |
2 |
right triceps brachii reflex |
present |
0 |
|
present with reinforcement |
1 |
|
absent |
2 |
left triceps brachii reflex |
present |
0 |
|
present with reinforcement |
1 |
|
absent |
2 |
right quadriceps femoris reflex |
present |
0 |
|
present with reinforcement |
1 |
|
absent |
2 |
left quadriceps femoris reflex |
present |
0 |
|
present with reinforcement |
1 |
|
absent |
2 |
right Achilles tendon reflex |
present |
0 |
|
present with reinforcement |
1 |
|
absent |
2 |
left Achilles tendon reflex |
present |
0 |
|
present with reinforcement |
1 |
|
absent |
2 |
where:
• In the 10 gram filament testing, the dorsum of the great toe is touched 10 times. The number of correct reports of touching is recorded.
sensory impairment subscore =
= SUM(points for sensory testing on left and right sides)
motor strength subscore =
= SUM(points for muscle strength testing on left and right sides)
reflex subscore =
= SUM(points for reflex testing on left and right sides)
clinical examination score =
= (points for sensory impairment) + (points for motor strength) + (points for reflexes)
Nerve Conduction Studies |
Finding |
Points |
---|---|---|
sural nerve |
normal |
0 |
|
abnormal |
1 |
peroneal motor |
normal |
0 |
|
abnormal |
1 |
median sensory |
normal |
0 |
|
abnormal |
1 |
median motor |
normal |
0 |
|
abnormal |
1 |
ulnar sensory |
normal |
0 |
|
abnormal |
1 |
abnormal nerve conduction studies =
= SUM(points for nerve conduction studies)
Interpretation:
• minimum score for clinical exam: 0
• maximum score for clinical exam: 46
• minimum score for nerve conduction studies: 0
• maximum score for nerve conduction studies: 5
• The higher the score, the greater the neuropathy.
Clinical Examination Score |
Neuropathy |
---|---|
0 – 6 |
no |
7 – 12 |
mild |
13 – 29 |
moderate |
30 - 46 |
severe |
Abnormal Nerve Conduction Score |
Neuropathy |
---|---|
0 – 1 |
no |
2 |
mild |
3 – 4 |
moderate |
5 |
severe |
Purpose: To evaluate a patient with diabetes for neuropathy using the Michigan Diabetic Neuopathy Score (MDNS).
Specialty: Neurology
Objective: severity, prognosis, stage, complications
ICD-10: E10, G59.0, G63.1,