Description

The Michigan Diabetic Neuropathy Score (MDNS) can be used to evaluate a patient with diabetes mellitus for peripheral neuropathy.  It can used in conjunction with screening tests such as the Michigan Neuropathy Screening Instrument (MNSI) to confirm the presence of a neuropathy. The score can be monitored over time to evaluate disease progression.


Clinical examination:

(1) sensory: vibration in great toe, touch with 10 gram filament, pin prick to great toe

(2) muscle strength: finger spread, great toe extension, ankle dorsiflexion

(3) reflex testing: biceps brachii, triceps brachii, quadriceps femoris, Achilles

 

Nerve conduction studies:

(1) sural nerve

(2) peroneal motor

(3) median sensory nerve

(4) median motor nerve

(5) ulnar sensory nerve

 

Clinical Examination Test

Finding

Points

vibration in right great toe

normal

0

 

decreased

1

 

absent

2

vibration in left great toe

normal

0

 

decreased

1

 

absent

2

10 gram filament test to right great toe

normal (8-10 of 10)

0

 

decreased (1-7 of 10)

1

 

absent (0 of 10)

2

10 gram filament test to left great toe

normal (8-10 of 10)

0

 

decreased (1-7 of 10)

1

 

absent (0 of 10)

2

pin prick to dorsum of right great toe

painful

0

 

not painful

2

pin prick to dorsum of left great toe

painful

0

 

not painful

2

right hand finger spread muscle strength

normal

0

 

mild to moderate

1

 

severe

2

 

absent

3

left hand finger spread muscle strength

normal

0

 

mild to moderate

1

 

severe

2

 

absent

3

right great toe extension muscle strength

normal

0

 

mild to moderate

1

 

severe

2

 

absent

3

left great toe extension muscle strength

normal

0

 

mild to moderate

1

 

severe

2

 

absent

3

right ankle dorsiflexion muscle strength

normal

0

 

mild to moderate

1

 

severe

2

 

absent

3

left ankle dorsiflexion muscle strength

normal

0

 

mild to moderate

1

 

severe

2

 

absent

3

right biceps brachii reflex

present

0

 

present with reinforcement

1

 

absent

2

left biceps brachii reflex

present

0

 

present with reinforcement

1

 

absent

2

right triceps brachii reflex

present

0

 

present with reinforcement

1

 

absent

2

left triceps brachii reflex

present

0

 

present with reinforcement

1

 

absent

2

right quadriceps femoris reflex

present

0

 

present with reinforcement

1

 

absent

2

left quadriceps femoris reflex

present

0

 

present with reinforcement

1

 

absent

2

right Achilles tendon reflex

present

0

 

present with reinforcement

1

 

absent

2

left Achilles tendon reflex

present

0

 

present with reinforcement

1

 

absent

2

 

where:

• In the 10 gram filament testing, the dorsum of the great toe is touched 10 times. The number of correct reports of touching is recorded.

 

sensory impairment subscore =

= SUM(points for sensory testing on left and right sides)

 

motor strength subscore =

= SUM(points for muscle strength testing on left and right sides)

 

reflex subscore =

=  SUM(points for reflex testing on left and right sides)

 

clinical examination score =

= (points for sensory impairment) + (points for motor strength) + (points for reflexes)

 

Nerve Conduction Studies

Finding

Points

sural nerve

normal

0

 

abnormal

1

peroneal motor

normal

0

 

abnormal

1

median sensory

normal

0

 

abnormal

1

median motor

normal

0

 

abnormal

1

ulnar sensory

normal

0

 

abnormal

1

 

abnormal nerve conduction studies =

= SUM(points for nerve conduction studies)

 

Interpretation:

• minimum score for clinical exam: 0

• maximum score for clinical exam: 46

• minimum score for nerve conduction studies: 0

• maximum score for nerve conduction studies: 5

• The higher the score, the greater the neuropathy.

 

Clinical Examination Score

Neuropathy

0 – 6

no

7 – 12

mild

13 – 29

moderate

30 - 46

severe

 

 

Abnormal Nerve Conduction Score

Neuropathy

0 – 1

no

2

mild

3 – 4

moderate

5

severe

 


To read more or access our algorithms and calculators, please log in or register.