StenoSCORE of Karaba et al for Predicting Stenotrophomonas maltophilia Bloodstream Infection in a Patient with a Hematologic Malignancy: Risk Score 2 (Automatic Variable Selection)
Karaba et al reported the StenoSCORE for predicting bloodstream infection with Stenotrophomonas maltophilia in a patient with a hematologic malignancy. There are 2 versions of the score - one knowledge-driven and the second based on automatic variable selection. The authors are from Johns Hopkins University.
Patient selection: hematologic malignancy, age >= 12 years
Parameters for automatic variable selection risk score:
(1) mucositis
(2) number of days with receipt of carbapenem
Parameter
Finding
beta-coefficient
mucositis
no
0
yes
1.41
carbapenem receipt
none or < 3 days
0
>= 3 days
1.50
value of X =
= SUM(points for all parameters) - 3.27
probability of Stenotrophomonas sepsis =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.63, which is less than that of the knowledge-driven score.
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