Cao et al reported a score for predicting survival benefit of palliative primary tumor resection for a patient with unresectable metastatic colorectal cancer. The authors are from Zhejiang University and associated hospitals in Hangzhou, China.
Patient selection: palliative primary tumor resection
Parameters:
(1) serum CEA in ng/mL
(2) serum CA19-9 in IU/mL
(3) serum LDH in U/L
(4) neutrophil-to-lymphocyte ratio (NLR)
Parameter
Finding
Points
serum CEA
<= 5 ng/mL
0
> 5 ng/mL
1
serum CA19-9
<= 37 IU/mL
> 37 IU/mL
serum LDH
<= 250 U/L
> 250 U/L
NLR
<= 5
> 5
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 4
Score
Risk Group
Median Overall Survival
low
52.1 months
1 or 2
intermediate
26.2 months
3 or 4
high
13.3 months
The overall survival was comparable for those who did not undergo surgery and for high-risk patients who did.
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Specialty: Hematology Oncology
