Poon et al reported risk factors for invasive Candidiasis in a patient who has undergone an intra-abdominal surgical procedure. The authors are from New York Presbyterian Hospital-Columbia in New York City.
Patient selection: status post intra-abdominal surgery, currently in the intensive care unit
Most common intra-abdominal procedures: bowel resection, bowel suture, open surgery with lavage
Candida species most often isolated: Candida albicans and Candida glabrata
Risk factors for invasive candidiasis from multivariate analysis:
(1) total parenteral nutrition (TPN, OR 4.7)
(2) Candida colonization (OR 8.0; to be of use there should be a preoperative surveillance protocol)
Prior antibiotic use was a risk factor in the univariate analysis.
A patient considered to be at increased risk may benefit from closer surveillance and prophylactic antifungal therapy.
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