Ishizuka et al used the Glasgow Prognostic Score (GPS) to evaluate patients with Stage IV colorectal cancer. This can be used before and after surgery to predict survival. The authors are from Dokkyo Medical University n Japan.
Parameters:
(1) C-reactive protein
(2) serum albumin
Parameter
Finding
Points
CRP
<= 10 mg/L
0
> 10 mg/L
1
serum albumin
>= 35 g/L
0
< 35 g/L
1
total score =
= SUM(points for both parameters)
Interpretation:
• minimum score: 0
• maximum score: 2
• The higher the score the greater the risk.
Additional risk factors:
(1) tumor pathology: tub1 or tub2 (well or moderately differentiated) vs other (poorly differentiated or undifferentiated)
(2) M1a (distant metastases to 1 organ) versus M1b (distant metastases to 2 or more organs)
Stage
GPS
50% Survival After Surgery
M1a
0 or 1
27 months
2
7 months
M1b
0
22 months
1
15 months
2
10 months
estimated from Figure 3 page 26
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