Are you evaluating a patient for microangiopathic hemolytic anemia?

Does the patient have?

• large numbers of schistocytes and red cell fragments in the peripheral blood smear?

• thrombocytopenia?

• a positive direct antiglobulin (Coombs) test?

• anemia?

• decreased serum haptoglobin?

• hemoglobinuria with urine hemosiderin?

• elevated serum LDH?

• reticulocytosis?

• elevated indirect serum bilirubin?

• a mechanical heart valve, chemical exposure or other explanation for hemolysis?


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