Spina et al reported the Elderly Prognostic Index for evaluating an older adult with diffuse large B-cell lymphoma (DLBCL). The authors are from multiple institutions in Italy and participants of the Fondazione Italiana Linfomi.
Patient selection: age >= 65 years of age with untreated de novo DLBCL
Parameters:
(1) simplified Comprehensive Geriatric Assessment (sCGA; defined in paper)
(2) International Prognostic Index (IPI) score, from 0 to 5
(3) hemoglobin in g/dL
Parameter
Finding
Points
sCGA group
Group 1
0
Group 2
2
Group 3
3
IPI
0 or 1
0
2
1
3 to 5
3
hemoglobin
>= 12 g/dL
0
< 12 g/dL
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 7
Score
Risk Group
3-Year Overall Survival
0 or 1
low
87%
2 to 4
intermediate
69%
5 to 7
high
42%
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